MON-040 CLINICAL PROFILE & OUTCOME OF IGA NEPHROPATHY PATIENTS

Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Background: IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. Objective: To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. Methods: Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. B...

Comment on: Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Patients with IgA Nephropathy

The actual state of IgA nephropathy in Japan was surveyed throughout the nation by a questionnaire. Five hundred patients were collected from 26 departments of pediatrics and 2,1 75 from 27 internal medicine. IgA nephropathy accounted for 19.2% of the children and 30.0% of the adults among primary glomerular diseases. Most of the patients, regardless children and adults, were detected by chance...

NF-kB Expression in IgA Nephropathy Outcome

Some studies have demonstrated the involvement of nuclear factor-kappa B (NF-kB) in the pathogenesis of glomerulonephritis. The aim of our study was twofold: (1) to analyze the prognostic value of NF-kB expression in primary IgA nephropathy (IgAN) and (2) to compare the results of NF-kB expression by immunohistochemistry (IHC) and southwestern histochemistry (SWH). We analyzed 62 patients diagn...

Clinical Profile &Treatment Outcome in Children with IgM Nephropathy

Introduction: IgM Nephropathy (IgMN) is a relatively new clinico-immunopathologic entity which presents as idiopathic nephrotic syndrome (NS) in children. Paediatric IgMN has a wide clinico-histopathological spectrum with ill-defined treatment options. Nephrologists often face a challenge in diagnosing and deciding the best treatment plan for these children. Methodology: This retrospective stud...